"I have never felt anything like the pump that I get out of Muscle Synergy. I ordered a case of it so I would be sure not to run out... Strength is going up and my waist is shrinking fast... "
"I am so happy that I took the chance with Muscle Synergy. In three months, I put on seven pounds of lean muscle tissue and even managed to lose five pounds of fat during my &building" program. I have never actually lost fat during a "building" phase before. My physique is filling out in all of the right areas... "
-Actual testimonials from Muscle Synergy users
Building and keeping muscle are 2 different processes Increasing the size of your muscles is as much about building muscle as it is keeping it. The nutritional needs of each process are different, something virtually all dietary supplements have overlooked.
'Hard gainer = 'Easy loser' Do you find it practically impossible to build muscle? If you miss meals or workouts, do your muscles 'deflate' all too quickly? Do you have poor circulation to your muscles? Do you find it difficult to get and keep a good 'pump'?
If you answered 'yes' to any of the above questions, then you probably find it very difficult to hold onto muscle. Indeed, 'hard gainer' is usually synonymous with 'easy loser'. Thus, even the subtlest inefficiency in the way you train or your approach to nutrition can cause the muscle you've worked so hard for to shrink, sometimes overnight.
If you were to be stranded on an island with all the food you could eat and all the weights you could lift, but only one supplement, Muscle Synergy would be the supplement of choice.
Muscle Synergy is giving 'hard gainers' and 'easy gainers' alike fantastic results because it uniquely attacks the challenge of gaining as well as keeping muscle from multiple angles. No other product on the market addresses the fact that muscle growth and muscle maintenance are two distinct processes characterized by distinct nutritional and non-nutritional needs.
"[After adding Muscle Synergy] I started leaning out... [but] people in the gym actually thought I was getting bigger... they were astonished. With Muscle Synergy I felt as if it kept my muscles fuller and more dense while my calories were cut...I could see a difference in my body day by day. I seemed to look better each day."
Niacin (nicotinic acid): Muscle Synergy releases into your body 200 mg of fast-acting niacin in the form of nicotinic acid (NA).
As many of you know all too well, hard gainers often have difficulty getting and keeping a good pump while working out. This can be attributed to inadequate muscle blood flow.
NA is well known for its 'global vasodilatory response', meaning it brings about a rapid increase in the diameter of your blood vessels (i.e., vasodilation), thereby promoting blood flow and overall vascularity. This makes getting and keeping a pump easier.
NA does more than increase blood flow. Though the matter is not without some controversy, anecdotal reports strongly suggest that growth hormone (GH) can enhance muscle size and overall leanness, even if only transiently. In fact, the results can be quite startling, with virtual 'transformations' occurring in as little as 48-72 hours. However, to achieve such effects typically requires injecting very high doses (e.g., 10-15 or more IU per day). This is very expensive; moreover, it does not mimic the normal pulsatile rhythm of GH secretion in humans. In addition, high-dose GH injections carry the risk of undesirable side effects.
In order to optimize muscle growth and fat loss, GH secretion must be stimulated in a pulsatile fashion for a long period of time - days to weeks. The resulting increases in circulating GH concentrations must be several-fold above normal.
Enter NA. NA reduces the release of fatty acids in the bloodstream, thereby alleviating their 'braking' effect on GH secretion. GH output is consequently increased several-fold, both at rest and in response to exercise (Murray et al., 1995).
"NA [nicotinic acid] in its various forms has gained much attention among both professionals and lay persons since its introduction in 1954 as a lipid-lowering agent. [5 and 6] It is now a well-established, FDA-approved first- or second-line therapy for all of the treatable disorders of lipid metabolism. It has been proved as a highly effective agent for reducing cholesterol, raising high density lipoprotein cholesterol, and lowering both low density lipoprotein cholesterol and triglycerides. In addition, it has the added benefits of lowering apolipoproteins A and B and fibrinogen and of raising growth hormone levels." From: Wolf et al. (2003)
A supplement containing niacin has recently been investigated for its ability to increase GH levels in healthy persons (Arwert et al., 2003). Dr. Jan Deijen, one of the scientists involved in the study, remarks "We only figured out that GH is increased by [the niacin-containing supplement] in healthy people but the physical consequences…are still unknown. There were, however, participants who reported that their muscle mass increased." (Deijen, 2004, personal communication.)
Creatine: As your muscles increase in size with your daily use of Muscle Synergy, they need to 'stock' more creatine. This puts a considerable demand on your body's creatine-synthesizing pathways, which Muscle Synergy helps to alleviate. Each serving contains 3000 mg of creatine.
Besides its well-known effects on muscle strength, power and work capacity, creatine promotes cell volumization ('swelling'). This potent anabolic signal accelerates glycogen synthesis (Robinson et al., 1999) and over muscle fiber size and thickness.
"My wife who rarely says anything about my contest prep, recently told me that she thought I was getting bigger. 7 lbs of lean mass, a 3rd place in my first pro show --yeah, I would say Muscle Synergy works. -Michael E.
Arginine: As noted above, the more muscle you gain, the greater the demand on creatine-synthesizing pathways to supply extra creatine to the newly added tissue. Arginine is required for the synthesis of creatine. Almost 2.5 grams of arginine are required to match the daily loss of creatine (as creatinine) in a 70-kg (~154-lb) male.
Skeletal muscle can represent anywhere from 40-50% or more of total body mass. Arginine is relatively abundant in muscle. Thus, if necessary, the breakdown of muscle protein can be relied on to meet your body's arginine needs. When used as directed, Muscle Synergy provides a whopping 7000 mg (7.0 grams) of arginine. That's more than enough arginine to make up for your daily loss of creatine. What remains can be used to provide the benefits discussed next.
In a frequently overlooked study performed Beaumier et al. (1995) fed healthy young adult males energy-balanced diets characterized as either 'normal' in arginine content (56.1 mg/kg/day) or 'arginine-supplemented' (561 mg/kg/day). Importantly, despite the fact that the nitrogen intake was the same for both groups, the arginine-supplemented group demonstrated an increase in nitrogen retention --a metabolic state of affairs generally regarded as very favorable for increasing the size of your muscles. Arginine supplementation was also associated with excretion of sodium and water.
Thus, arginine may enhance your ability to build muscle while fighting water retention (i.e., lean hard gains, as opposed to that bloated, or 'puffy', look). This is consistent with the frequent reports by Muscle Synergy users of increased muscle hardness and density -in addition to overall muscle size.
"Orally administered arginine hydrochloride certainly has anabolic effects by increasing insulin secretion. This molecule has been often used for its anti-asthenic effects in convalescent patients. Weight gain often occurs in patients receiving this therapy. This weight gain is often considered to be a side effect but is to be taking into account when arginine is consumed." From: Arginine researcher Dr. Adrien Schaefer (Schaefer, 2004; personal communication)
HMB: Each serving of new Muscle Synergy delivers 3000 mg (3.0 grams) of beta-hydroxy-beta-methylbutyrate (HMB). The purpose of HMB is summarized nicely by the title of a recent scientific paper on this compound, "Supplementing with beta-hydroxy-beta-methylbutyrate (HMB) to build and maintain muscle mass." (Alon et al., 2002).
In a nutshell, HMB helps protect your muscles from excess protein breakdown, thereby allowing you to avoid the frustrating '2 steps forward (gain), 1 step back (lose)' syndrome so common with hard gainers.
Tyrosine (2000 mg per serving): The faster and harder you work your muscles, the more you deplete your nervous system of neurotransmitters, certain of which (e.g., norepinephrine) are made from tyrosine.
Each serving of new Muscle Synergy supports the rapid replenishment of tyrosine-based neurotransmitters, allowing you to 'zap' your muscles into growth workout after workout with less risk of 'electrochemical exhaustion'.
The effects of tyrosine are strengthened even further with the addition of Rhodiola rosea (205 mg per serving; 3% rosavins, 1% salidroside) a performance-enhancing plant medicine of European and Mongolian origins that provides what users describe as 'pleasant, stress-relieving' benefits along with a jitter-free mental 'edge' that has to be experienced to be fully appreciated.
Muscle Synergy is the only formula designed to address the needs of both muscle building and muscle maintenance, thereby allowing you to accumulate muscle mass and strength faster than ever before. This is essential for the hard gainer or drug-free bodybuilder.
Don't fall behind any longer. Invest in your cycle of Muscle Synergy today.
REFERENCES Alon T, Bagchi D, Preuss HG. (2002). Supplementing with beta-hydroxy-beta-methylbutyrate (HMB) to build and maintain muscle mass: a review. Res Commun Mol Pathol Pharmacol, 111 (1-4): 139. Arwert LI, Deijen JB, Drent ML (2003). Effects of an oral mixture containing glycine, glutamine and niacin on memory, GH and IGF-I secretion in middle-aged and elderly subjects. Nutr Neurosci, 6(5): 269. Beaumier L, Castillo L, Ajami AM, Young VR (1995). Urea cycle intermediate kinetics and nitrate excretion at normal and "therapeutic" intakes of arginine in humans. Am J Physiol, 269: E884. Deijen JB (2004). Personal communication. Dr. Deijen was referring to the patients in the study he performed with Arwert and co-workers (Arwert et al., 2003, above). Murray R, Bartoli WP, Eddy DE, Horn MK (1995). Physiological and performance responses to nicotinic-acid ingestion during exercise. Med Sci Sports Exerc, 27(7): 1057. Robinson TM, Sewell DA, Hultman E, Greenhaff PA (1999). Role of submaximal exercise in promoting creatine and glycogen accumulation in human skeletal muscle. J Appl Physiol, 87: 598. Wolf R, Orion E, Matz H et al. (2003). Miscellaneous treatments, II: niacin and heparin: unapproved uses, dosages, or indications. Clinics in Dermatology, 20(5): 547.